Type 3 Fibroblast Growth Factor Receptor

A fibroblast growth factor receptor that regulates CHONDROCYTE growth and CELL DIFFERENTIATION. Mutations in the gene for fibroblast growth factor receptor 3 have been associated with ACHONDROPLASIA; THANATOPHORIC DYSPLASIA and NEOPLASTIC CELL TRANSFORMATION.

Also Known As:

Fibroblast Growth Factor Receptor 3; Receptor, Fibroblast Growth Factor, Type 3; CD333 Antigen; FGFR3 Protein; Fibroblast Growth Factor Receptors 3; Receptor 3, Fibroblast Growth Factor; Antigen, CD333

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein-Tyrosine Kinases: 7697
        Receptor Protein-Tyrosine Kinases: 5999
        Type 3 Fibroblast Growth Factor Receptor: 533
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Receptor Protein-Tyrosine Kinases: 5999
        Type 3 Fibroblast Growth Factor Receptor: 533
      - Peptide Receptors: 1159
        Growth Factor Receptors: 2663
        Fibroblast Growth Factor Receptors: 1599
        Type 3 Fibroblast Growth Factor Receptor: 533
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7697
      - Receptor Protein-Tyrosine Kinases: 5999
        Type 3 Fibroblast Growth Factor Receptor: 533
  - Neoplasm Proteins: 2
    - Oncogene Proteins: 7793
      - Proto-Oncogene Proteins: 7
        Type 3 Fibroblast Growth Factor Receptor: 533

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Disease

Drug/Important Bio-Agent (IBA)